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Creatine formulations and repeated sprint training: effects on physical and physiological adaptations in soccer players during the short-term preparation phase.

Duan C, Wang Z, Wang Q. · Journal of the International Society of Sports Nutrition · 2026

This study compared four groups of college soccer players—three taking different types of creatine supplements and one taking placebo—over a 4-week training program with repeated sprint drills, measuring their improvements in jumping, sprinting, and power output. All supplement groups improved more than placebo, with creatine ethyl ester and creatine hydrochloride forms showing the best gains in vertical jump, sprint speed, running agility, and peak power output.
Takeaway: Consider creatine ethyl ester or hydrochloride forms over standard monohydrate if you're looking to maximize short-term improvements in jumping and sprinting performance during focused training blocks.
Abstract (source)

Background: This research examined the impact of various creatine (Cr) supplementation formulations during a 4-week preparatory phase on the efficacy of repeated sprint training (RST) and on improvements in physical and physiological performance in male soccer athletes.

Methods: A total of forty collegiate young soccer players volunteered for the study. They were randomly divided into four groups: creatine monohydrate (Cr-Mon, n = 10), creatine ethyl ester (Cr-Ee, n = 10), creatine hydrochloride (Cr-Hcl, n = 10), and placebo (PL, n = 10). All athletes engaged in a 4-week training intervention, three times a week (i.e. 12 sessions), and physical (countermovement vertical jump [CMVJ], 20-m sprint, and L-run) and physiological (Wingate anaerobic power and incremental exercise tests) performance were assessed both before and after the training period.

Results: All training groups improved physical and physiological performance following the 4-week intervention period ( p p = 0.001) in physical performance, peak power output, and fatigue index compared to the PL group. However, no significant differences were found among the groups regarding mean power output and VO2max. Notably, the Ee and Hcl forms of Cr showed superior gains ( p

Conclusions: The

results underscore the importance of Cr ingestion in enhancing adaptations for short-term physical performance tasks, highlighting the effectiveness of the Ee and Hcl forms in further improving the CMVJ, 20-m sprint, L-run, and peak power among soccer players during the short-term preparation phase.

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